DSc, Universidade Estadual Paulista – Jaboticabal (UNESP), Brazil, 2015
My current research focuses on investigating the efficacy and toxicity of maltose-conjugated and PEG-conjugate antimicrobial agents used to treat urinary tract infections (UTI) and bloodstream infection (BSI) caused by Escherichia coli. My work is performed in collaboration with a bioengineering lab, here at UC Berkeley. This new drug delivery system enhances the transport of antimicrobial agents, into gram negative bacteria, by conjugating drugs to molecules that enable them to be delivered to patients at higher doses than free-drugs, thus maintaining a therapeutic concentration in the serum for an extended period of time without causing toxicity. The conjugation strategies we are developing have the potential to significantly improve the treatment of bacterial infections.