BS, Microbiology, San Jose State University, 2010
MS, Microbiology and Molecular Biology, San Jose State University, 2012
My main research interest is antimicrobial resistance in Gram-negative bacteria. My current research projects focus on bacterial resistance through the production of β-lactamases—enzymes that hydrolyze and inactivate β-lactam antibiotics. I am investigating the use of antibody-based methods for the rapid detection of β-lactamases in Gram-negative bacteria that cause urinary tract infections. This work focuses on detection of a variety of clinically relevant β-lactamases and is performed in collaboration with a research corporation. I am also investigating the use of antibody-based methods to inactivate the β-lactamases produced by Gram-negative bacteria, as a way to curb their resistance. This project currently focuses on inactivation of the NDM-1 carbapenemase. In addition, I am exploring the role of the regulation of outer membrane porins in increased resistance to β-lactams in Klebsiella pneumoniae vs. Escherichia coli.